Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
IL2 | P60568 | interleukin 2 | 0.48 | 0.336 | 0.885 | |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
HMGB1 | P09429 | high mobility group box 1 | Nucleic acid binding | 0.82 | 0.368 | 0.923 |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
LEPR | P48357 | leptin receptor | Signaling | 0.99 | 0.433 | 0.808 |
MEFV | O15553 | MEFV innate immuity regulator, pyrin | 1.0E-14 | 0.440 | 0.885 | |
HSPD1 | P10809 | heat shock protein family D (Hsp60) member 1 | 0.99 | 0.432 | 0.808 | |
ADA | P00813 | adenosine deaminase | Enzyme | 2.9E-12 | 0.440 | 0.885 |